The Guadalupe on Main

The Guadalupe on Main Family owned modern southwest cusine with flavors from Jalisco Mexico. Craft cocktails and mixology is our specialty.
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Relaxing and colorful atmosphere will make it hard to leave.

✨️ Weekend Cocktail Specials ✨️Come see what Haylee & Jared mixed up for the weekend!
05/22/2026

✨️ Weekend Cocktail Specials ✨️

Come see what Haylee & Jared mixed up for the weekend!

Time for another Test Kitchen with Chef Jhomeny Ramos! We invite you to join us for this special three-course dinner, in...
05/14/2026

Time for another Test Kitchen with Chef Jhomeny Ramos! We invite you to join us for this special three-course dinner, in collaboration with another award-winning local chef, CJ Kahley.

Get your tickets now!

Chef's Test Kitchen @ Guadalupe on Main - https://share.google/BrkMarZqzX8sRku5W

05/08/2026

So excited to introduce .14 and welcome him to our team. ❤️

04/26/2026

Happy Sunday

04/20/2026

Closed Mondays & Tuesdays yall….

04/19/2026

Arizona summers be like…

04/17/2026

How many Mole Enchiladas do you think we are gonna sell today?

Address

1526 E Main Street
Mesa, AZ
85204

Opening Hours

Wednesday 11am - 10pm
Thursday 11am - 10pm
Friday 11am - 11pm
Saturday 11am - 11pm
Sunday 11am - 9pm

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